| Item Type | Name |
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Concept
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Exocytosis
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Concept
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Genes, Regulator
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Concept
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Gene Expression Regulation
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Concept
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Regulatory Sequences, Nucleic Acid
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Concept
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Gene Expression Regulation, Developmental
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Concept
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Gene Regulatory Networks
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Concept
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Cystic Fibrosis Transmembrane Conductance Regulator
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Concept
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Sterol Regulatory Element Binding Protein 1
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Concept
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Regulatory Elements, Transcriptional
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Concept
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Down-Regulation
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Concept
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Gene Expression Regulation, Neoplastic
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Academic Article
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Coalescent-based association mapping and fine mapping of complex trait loci.
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Academic Article
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Understanding mechanisms underlying human gene expression variation with RNA sequencing.
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Academic Article
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Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data.
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Academic Article
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Gene expression levels are a target of recent natural selection in the human genome.
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Academic Article
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Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data.
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Academic Article
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Genomics: ENCODE explained.
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Academic Article
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Dissecting the regulatory architecture of gene expression QTLs.
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Academic Article
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The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels.
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Academic Article
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Revealing the architecture of gene regulation: the promise of eQTL studies.
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Academic Article
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DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines.
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Academic Article
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Clonal origin and evolution of a transmissible cancer.
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Academic Article
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DNase?I sensitivity QTLs are a major determinant of human expression variation.
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Academic Article
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High-resolution mapping of expression-QTLs yields insight into human gene regulation.
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Academic Article
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Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.
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Academic Article
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Epigenetic modifications are associated with inter-species gene expression variation in primates.
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Academic Article
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Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature.
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Academic Article
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The genetic and mechanistic basis for variation in gene regulation.
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Academic Article
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Genomic variation. Impact of regulatory variation from RNA to protein.
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Academic Article
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Identification of genetic variants that affect histone modifications in human cells.
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Academic Article
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Primate transcript and protein expression levels evolve under compensatory selection pressures.
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Academic Article
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The chromatin architectural proteins HMGD1 and H1 bind reciprocally and have opposite effects on chromatin structure and gene regulation.
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Academic Article
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The functional consequences of variation in transcription factor binding.
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Academic Article
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Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions.
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Academic Article
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msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding.
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Academic Article
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Abundant contribution of short tandem repeats to gene expression variation in humans.
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Academic Article
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Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs.
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Academic Article
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RNA splicing is a primary link between genetic variation and disease.
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Academic Article
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Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals.
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Academic Article
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Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice.
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Academic Article
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Whole Genome Sequencing Identifies a Novel Factor Required for Secretory Granule Maturation in Tetrahymena thermophila.
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Academic Article
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Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution.
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Academic Article
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Impact of regulatory variation across human iPSCs and differentiated cells.
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Academic Article
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Post-translational buffering leads to convergent protein expression levels between primates.
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Academic Article
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Remodeling the Specificity of an Endosomal CORVET Tether Underlies Formation of Regulated Secretory Vesicles in the Ciliate Tetrahymena thermophila.
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Academic Article
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High-resolution mapping of cancer cell networks using co-functional interactions.
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Academic Article
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Trans Effects on Gene Expression Can Drive Omnigenic Inheritance.
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Academic Article
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Landscape of stimulation-responsive chromatin across diverse human immune cells.
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Academic Article
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Chromatin accessibility dynamics in a model of human forebrain development.
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Academic Article
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A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density.
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Academic Article
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Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.
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Academic Article
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Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks.
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Grant
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Statistical analysis of gene expression quantitative trait loci (eQTL)
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Grant
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Decoding the regulatory architecture of the human genome across cell types, individuals and disease
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Grant
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Computational methods for modeling lineage-specific gene regulation
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Grant
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Analysis and interpretation of noncoding regulatory variation
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Grant
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Genetic and epigenetic controls of gene regulation
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Grant
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Integration of functional data and GWAS to elucidate genetic basis of diseases
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Academic Article
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Precise modulation of transcription factor levels identifies features underlying dosage sensitivity.
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Academic Article
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Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease.
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Academic Article
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Systematic differences in discovery of genetic effects on gene expression and complex traits.
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Academic Article
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The functional impact of rare variation across the regulatory cascade.
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